How do you take meds for Eosinophilic Esophagitis?

Splenda packets sticks yellow
I was diagnosed with Eosinophilic Esophagitis (EoE) this summer, which is an allergic condition involving difficulty swallowing and narrowing of the esophagus due to the presence of eosinophils in the esophageal tissue. Ordinarily, these inflammatory lymphocytes would not be present in the tissue of the esophagus, however some people with food allergies may develop this condition. It has ties to asthma, which is another condition where eosinophils collect where they’re not supposed to be.

There is no officially approved medication for treating EoE but many studies have shown improvement for those swallowing a viscous solution of corticosteriods, which are used for asthma treatment, though modified so they will coat the throat instead of heading down into the lungs. My doctor prescribed me the most commonly used one, budesonide 0.5mg, which are in the form used in a nebulizer for asthma. Everything I’ve read online in case studies shows that this form is mixed with 5 packets of sucralose sweetener and then swallowed, with nothing else taken by mouth for 30 minutes after.

Success rates or abatement of symptoms is very good, up in the 80% range in the studies I read, so I’m confident in trying this method. But I’m not sure about making this viscous solution, as I can’t see how the ampule of budesonide (it contains 2ml of fluid) could mix with 5 packets of sucralose (aka Splenda) and make a swallowable concoction. I also don’t like the taste of Splenda, so I’m wondering if there’s another sweetener or substance I can mix this with to try it out.

Basically, I’m afraid I’ll end up with a mouthful of bitter stuff and a numb tongue, as I did when I tried to dry-swallow a standard inhaler. So I’m wondering if anyone else has any suggestions or has tried a similar treatment? Do you have any pointers?

PS: just found this video on YouTube showing a mom preparing the viscous budesonide for her son. It looks like a “snowball” (as she calls it) which is very different from how I interpreted it from instructions. Thank you, YouTube!

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